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Insertion of retrovirus into the first intron of alpha 1(I) collagen gene to embryonic lethal mutation in mice.

Integration of the Moloney murine leukemia virus (M-MuLV) into the germ line of Mov-13 mice blocked formation of stable alpha 1(I) collagen mRNA and led to an embryonic lethal mutation. A 14-kilobase fragment representing the integration site of the virus was molecularly cloned and identified as the...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Harbers, K, Kuehn, M, Delius, H, Jaenisch, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1984
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344865/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6324198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.5.1504
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