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Molecular Characterization of the viaB Locus Encoding the Biosynthetic Machinery for Vi Capsule Formation in Salmonella Typhi

The Vi capsular polysaccharide (CPS) of Salmonella enterica serovar Typhi, the cause of human typhoid, is important for infectivity and virulence. The Vi biosynthetic machinery is encoded within the viaB locus composed of 10 genes involved in regulation of expression (tviA), polymer synthesis (tviB-...

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Main Authors: Wetter, Michael, Goulding, David, Pickard, Derek, Kowarik, Michael, Waechter, Charles J., Dougan, Gordon, Wacker, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448643/
https://ncbi.nlm.nih.gov/pubmed/23029132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045609
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