A Salmonella Typhimurium-Typhi Genomic Chimera: A Model to Study Vi Polysaccharide Capsule Function In Vivo

The Vi capsular polysaccharide is a virulence-associated factor expressed by Salmonella enterica serotype Typhi but absent from virtually all other Salmonella serotypes. In order to study this determinant in vivo, we characterised a Vi-positive S. Typhimurium (C5.507 Vi(+)), harbouring the Salmonell...

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Bibliographic Details
Main Authors: Jansen, Angela M., Hall, Lindsay J., Clare, Simon, Goulding, David, Holt, Kathryn E., Grant, Andrew J., Mastroeni, Piero, Dougan, Gordon, Kingsley, Robert A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145788/
https://ncbi.nlm.nih.gov/pubmed/21829346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002131
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