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Src Homology-2 Domain-Containing Protein Tyrosine Phosphatase (SHP) 2 and p38 Regulate the Expression of Chemokine CXCL8 in Human Astrocytes

CXCL8, one of the first chemokines found in the brain, is upregulated in the brains and cerebrospinal fluid of HIV-1 infected individuals suggesting its potential role in human immune deficiency virus (HIV)-associated neuroinflammation. Astrocytes are known to be the major contributors to the CXCL8...

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Autors principals: Mamik, Manmeet K., Ghorpade, Anuja
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448633/
https://ncbi.nlm.nih.gov/pubmed/23029125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045596
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