Repeated Assessment by High-Throughput Assay Demonstrates that Sperm DNA Methylation Levels Are Highly Reproducible

OBJECTIVE: To assess reliability of high-throughput assay of sperm DNA methylation. DESIGN: Observational study comparing DNA methylation of sperm isolated from three divided and twelve longitudinally collected semen samples. SETTING: Academic Medical Center PATIENTS: One man undergoing screening se...

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Bibliographic Details
Main Authors: Cortessis, Victoria K., Siegmund, Kimberly, Houshdaran, Sahar, Laird, Peter W., Sokol, Rebecca Z.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448450/
https://ncbi.nlm.nih.gov/pubmed/22035967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fertnstert.2011.09.036
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