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Trauma patients’ elevated Tumor Necrosis Related Apoptosis Inducing Ligand (TRAIL) contributes to increased T cell apoptosis

Immunosuppression resulting from excessive post-trauma apoptosis of hyperactivated Tcells is controversial. TRAIL mediated Tcell apoptosis decreases highly activated Tcells’ responses. Caspase-10, a particular TRAIL target, was increased in trauma patients’ Tcells with concomitantly elevated plasma...

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Detalhes bibliográficos
Main Authors: Bandyopadhyay, Gautam, Bankey, Paul E., Miller-Graziano, Carol L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448438/
https://ncbi.nlm.nih.gov/pubmed/22926077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2012.07.010
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