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MDM2 and MDMX: Alone and together in regulation of p53

p53, a critical tumor suppressor, is activated by various cellular stresses to prevent and repair damages that can lead to tumor development. In response to these stresses, p53 activation can cause very serious cellular effects including permanent cell cycle arrest and cell death. p53 must therefore...

詳細記述

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書誌詳細
主要な著者: Shadfan, Miriam, Lopez-Pajares, Vanessa, Yuan, Zhi-Min
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448287/
https://ncbi.nlm.nih.gov/pubmed/23002429
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