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MDM2 and MDMX: Alone and together in regulation of p53

p53, a critical tumor suppressor, is activated by various cellular stresses to prevent and repair damages that can lead to tumor development. In response to these stresses, p53 activation can cause very serious cellular effects including permanent cell cycle arrest and cell death. p53 must therefore...

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Bibliografski detalji
Glavni autori: Shadfan, Miriam, Lopez-Pajares, Vanessa, Yuan, Zhi-Min
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448287/
https://ncbi.nlm.nih.gov/pubmed/23002429
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