B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways

Recent data reveal an important role for B cells in the pathogenesis of chronic GVHD (cGVHD). Patients with cGVHD have delayed B-cell reconstitution and elevated BAFF to B-cell ratios compared to patients without cGVHD. The mechanisms promoting and sustaining B-cell activation in this disease, howev...

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Bibliografiset tiedot
Päätekijät: Allen, Jessica L., Fore, Matthew S., Wooten, Jenna, Roehrs, Philip A., Bhuiya, Nazmim S., Hoffert, Todd, Sharf, Andrew, Deal, Allison M., Armistead, Paul, Coghill, James, Gabriel, Don A., Irons, Robert, Essenmacher, Amber, Shea, Thomas C., Richards, Kristy, Cutler, Corey, Ritz, Jerome, Serody, Jonathan, Baldwin, Albert S., Sarantopoulos, Stefanie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Transplantation
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448264/
https://ncbi.nlm.nih.gov/pubmed/22896003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-438911
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