Munc18b/STXBP2 is required for platelet secretion

Platelets are vital for hemostasis because they release their granule contents in response to vascular damage. Platelet exocytosis is mediated by soluble N-ethylmaleimide–sensitive factor attachment protein receptors (SNAREs), whose interactions are governed by regulators, eg, Sec/Munc18 proteins. T...

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Autors principals: Al Hawas, Rania, Ren, Qiansheng, Ye, Shaojing, Karim, Zubair A., Filipovich, Alexandra H., Whiteheart, Sidney W.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448261/
https://ncbi.nlm.nih.gov/pubmed/22791290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-430629
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