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Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat

Genome-wide association studies have identified SNPs reproducibly associated with type 2 diabetes (T2D). We examined the effect of genetic predisposition to T2D on insulin sensitivity and secretion using detailed phenotyping in overweight individuals with no diagnosis of T2D. Furthermore, we investi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Walker, Celia G., Loos, Ruth J. F., Mander, Adrian P., Jebb, Susan A., Frost, Gary S., Griffin, Bruce A., Lovegrove, Julie A., Sanders, Thomas A. B., Bluck, Les J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer-Verlag 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448035/
https://ncbi.nlm.nih.gov/pubmed/22350825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12263-012-0284-8
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