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Enzymatic Excision of Uracil Residues in Nucleosomes Depends on Local DNA Structure and Dynamics
The excision of uracil bases from DNA is accomplished by the enzyme uracil DNA glycosylase (UNG). Recognition of uracil bases in free DNA is facilitated by uracil base pair dynamics, but it is not known whether this same mechanistic feature is relevant for detection and excision of uracil residues e...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3448002/ https://ncbi.nlm.nih.gov/pubmed/22784353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3006412 |
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