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IgM in a human neuropathy related to paraproteinemia binds to a carbohydrate determinant in the myelin-associated glycoprotein and to a ganglioside.

The IgM in three patients with paraproteinemia and peripheral neuropathy was shown to bind to human myelin-associated glycoprotein (MAG) that had been purified to homogeneity by gel filtration on Sepharose CL-6B. The antigenic determinant reacting with the IgM from all three patients was in the carb...

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Autors principals: Ilyas, A A, Quarles, R H, MacIntosh, T D, Dobersen, M J, Trapp, B D, Dalakas, M C, Brady, R O
Format: Artigo
Idioma:Inglês
Publicat: 1984
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC344799/
https://ncbi.nlm.nih.gov/pubmed/6199795
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