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The role of sulfoglucuronosyl glycosphingolipids in the pathogenesis of monoclonal IgM paraproteinemia and peripheral neuropathy

In IgM paraproteinemia and peripheral neuropathy, IgM M-protein secretion by B cells leads to a T helper cell response, suggesting that it is antibody-mediated autoimmune disease involving carbohydrate epitopes in myelin sheaths. An immune response against sulfoglucuronosyl glycosphingolipids (SGGLs...

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書目詳細資料
主要作者: ARIGA, Toshio
格式: Artigo
語言:Inglês
出版: The Japan Academy 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171285/
https://ncbi.nlm.nih.gov/pubmed/21785257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.87.386
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