Thymic T cells are driven to expand upon interaction with self-class II major histocompatibility complex gene products on accessory cells.

Murine thymocytes induce the monokine interleukin 1 upon in vitro coculture with a radioresistant Ia-bearing accessory cell [murine Ia molecule is a class II major histocompatibility complex (MHC) antigen]. The generation of interleukin 1 is critically dependent on the function of I-region gene prod...

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Bibliographic Details
Main Authors: Rock, K L, Benacerraf, B
Format: Artigo
Language:Inglês
Published: 1984
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC344798/
https://ncbi.nlm.nih.gov/pubmed/6608107
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