The role of peptides in thymic positive selection of class II major histocompatibility complex-restricted T cells

A thymic epithelial cell line transfected with I-E(k) was used in reaggregate cultures to study the role of peptides in positive selection of T cell receptor transgenic thymocytes. In this system, positive selection of CD4 SP cells occurred only after the addition of exogenous peptide. Analysis of a...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wang, Rongfang, Nelson, Andrew, Kimachi, Kazuhiko, Grey, Howard M., Farr, Andrew G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3804
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