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Thymic T cells are driven to expand upon interaction with self-class II major histocompatibility complex gene products on accessory cells.
Murine thymocytes induce the monokine interleukin 1 upon in vitro coculture with a radioresistant Ia-bearing accessory cell [murine Ia molecule is a class II major histocompatibility complex (MHC) antigen]. The generation of interleukin 1 is critically dependent on the function of I-region gene prod...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1984
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC344798/ https://ncbi.nlm.nih.gov/pubmed/6608107 |
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