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Structural Investigation of MscL Gating Using Experimental Data and Coarse Grained MD Simulations

The mechanosensitive channel of large conductance (MscL) has become a model system in which to understand mechanosensation, a process involved in osmoregulation and many other physiological functions. While a high resolution closed state structure is available, details of the open structure and the...

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Main Authors: Deplazes, Evelyne, Louhivuori, Martti, Jayatilaka, Dylan, Marrink, Siewert J., Corry, Ben
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447979/
https://ncbi.nlm.nih.gov/pubmed/23028281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002683
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