Ephrin-B2–Activated Peripheral Blood Mononuclear Cells From Diabetic Patients Restore Diabetes-Induced Impairment of Postischemic Neovascularization

We hypothesized that in vitro treatment of peripheral blood mononuclear cells (PB-MNCs) from diabetic patients with ephrin-B2/Fc (EFNB2) improves their proangiogenic therapeutic potential in diabetic ischemic experimental models. Diabetes was induced in nude athymic mice by streptozotocin injections...

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Detalhes bibliográficos
Main Authors: Broquères-You, Dong, Leré-Déan, Carole, Merkulova-Rainon, Tatiana, Mantsounga, Chris S., Allanic, David, Hainaud, Patricia, Contrères, Jean-Olivier, Wang, Yu, Vilar, José, Virally, Marie, Mourad, Jean-Jacques, Guillausseau, Pierre-Jean, Silvestre, Jean-Sébastien, Lévy, Bernard I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Pharmacology and Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447889/
https://ncbi.nlm.nih.gov/pubmed/22596048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1768
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