NADPH Oxidase-Derived Overproduction of Reactive Oxygen Species Impairs Postischemic Neovascularization in Mice with Type 1 Diabetes

We hypothesized that diabetes-induced oxidative stress may affect postischemic neovascularization. The response to unilateral femoral artery ligation was studied in wild-type or gp91(phox)-deficient control or type 1 diabetic mice or in animals treated with the anti-oxidant N-acetyl-l-cysteine (NAC)...

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Main Authors: Ebrahimian, Téni G, Heymes, Christophe, You, Dong, Blanc-Brude, Olivier, Mees, Barend, Waeckel, Ludovic, Duriez, Micheline, Vilar, José, Brandes, Ralph P., Levy, Bernard I., Shah, Ajay M., Silvestre, Jean-Sébastien
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698801/
https://ncbi.nlm.nih.gov/pubmed/16877369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060042
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