The Cardiac Ventricular 5-HT(4) Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure

A positive inotropic responsiveness to serotonin, mediated by 5-HT(4) and 5-HT(2A) receptors, appears in the ventricle of rats with post-infarction congestive heart failure (HF) and pressure overload-induced hypertrophy. A hallmark of HF is a transition towards a foetal genotype which correlates wit...

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Detalhes bibliográficos
Main Authors: Brattelid, Trond, Qvigstad, Eirik, Moltzau, Lise R., Bekkevold, Silje V. S., Sandnes, Dagny L., Birkeland, Jon Arne K., Skomedal, Tor, Osnes, Jan-Bjørn, Sjaastad, Ivar, Levy, Finn Olav
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447799/
https://ncbi.nlm.nih.gov/pubmed/23029047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045489
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