Expression of the Human Glucokinase Gene: Important Roles of the 5′ Flanking and Intron 1 Sequences

BACKGROUND: Glucokinase plays important tissue-specific roles in human physiology, where it acts as a sensor of blood glucose levels in the pancreas, and a few other cells of the gut and brain, and as the rate-limiting step in glucose metabolism in the liver. Liver-specific expression is driven by o...

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Detalhes bibliográficos
Main Authors: Wang, Yi, Guo, Tingting, Zhao, Shuyong, Li, Zhixin, Mao, Yiqing, Li, Hui, Wang, Xi, Wang, Rong, Xu, Wei, Song, Rongjing, Jin, Ling, Li, Xiuli, Irwin, David M., Niu, Gang, Tan, Huanran
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447760/
https://ncbi.nlm.nih.gov/pubmed/23029263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045824
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