The Genomic Landscape of TP53 and p53 Annotated High Grade Ovarian Serous Carcinomas from a Defined Founder Population Associated with Patient Outcome

High-grade ovarian serous carcinomas (HGSC) are characterized by TP53 mutations and non-random patterns of chromosomal anomalies, where the nature of the TP53 mutation may correlate with clinical outcome. However, the frequency of common somatic genomic events occurring in HGSCs from demographically...

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Main Authors: Wojnarowicz, Paulina M., Oros, Kathleen Klein, Quinn, Michael C. J., Arcand, Suzanna L., Gambaro, Karen, Madore, Jason, Birch, Ashley H., de Ladurantaye, Manon, Rahimi, Kurosh, Provencher, Diane M., Mes-Masson, Anne-Marie, Greenwood, Celia M. T., Tonin, Patricia N.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447752/
https://ncbi.nlm.nih.gov/pubmed/23029043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045484
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