ReQON: a Bioconductor package for recalibrating quality scores from next-generation sequencing data

BACKGROUND: Next-generation sequencing technologies have become important tools for genome-wide studies. However, the quality scores that are assigned to each base have been shown to be inaccurate. If the quality scores are used in downstream analyses, these inaccuracies can have a significant impac...

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Bibliografske podrobnosti
Main Authors: Cabanski, Christopher R, Cavin, Keary, Bizon, Chris, Wilkerson, Matthew D, Parker, Joel S, Wilhelmsen, Kirk C, Perou, Charles M, Marron, JS, Hayes, D Neil
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
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Software
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447716/
https://ncbi.nlm.nih.gov/pubmed/22946927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-221
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