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ReQON: a Bioconductor package for recalibrating quality scores from next-generation sequencing data

BACKGROUND: Next-generation sequencing technologies have become important tools for genome-wide studies. However, the quality scores that are assigned to each base have been shown to be inaccurate. If the quality scores are used in downstream analyses, these inaccuracies can have a significant impac...

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Detalhes bibliográficos
Main Authors: Cabanski, Christopher R, Cavin, Keary, Bizon, Chris, Wilkerson, Matthew D, Parker, Joel S, Wilhelmsen, Kirk C, Perou, Charles M, Marron, JS, Hayes, D Neil
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447716/
https://ncbi.nlm.nih.gov/pubmed/22946927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-221
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