Reduced osteoblast activity in the mice lacking TR4 nuclear receptor leads to osteoporosis

BACKGROUND: Early studies suggested that TR4 nuclear receptor might play important roles in the skeletal development, yet its detailed mechanism remains unclear. METHODS: We generated TR4 knockout mice and compared skeletal development with their wild type littermates. Primary bone marrow cells were...

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Bibliographische Detailangaben
Hauptverfasser: Lin, Shin-Jen, Ho, Hsin-Chiu, Lee, Yi-Fen, Liu, Ning-Chun, Liu, Su, Li, Gonghui, Shyr, Chih-Rong, Chang, Chawnshang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447707/
https://ncbi.nlm.nih.gov/pubmed/22676849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-10-43
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