Premature aging with impaired oxidative stress defense in mice lacking TR4

Early studies suggest that TR4 nuclear receptor is a key transcriptional factor regulating various biological activities, including reproduction, cerebella development, and metabolism. Here we report that mice lacking TR4 (TR4(−/−)) exhibited increasing genome instability and defective oxidative str...

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Détails bibliographiques
Auteurs principaux: Lee, Yi-Fen, Liu, Su, Liu, Ning-Chun, Wang, Ruey-Sheng, Chen, Lu-Min, Lin, Wen-Jye, Ting, Huei-Ju, Ho, Hsin-Chiu, Li, Gonghui, Puzas, Edward J., Wu, Qiao, Chang, Chawnshang
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129845/
https://ncbi.nlm.nih.gov/pubmed/21521714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00701.2010
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