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Premature aging with impaired oxidative stress defense in mice lacking TR4
Early studies suggest that TR4 nuclear receptor is a key transcriptional factor regulating various biological activities, including reproduction, cerebella development, and metabolism. Here we report that mice lacking TR4 (TR4(−/−)) exhibited increasing genome instability and defective oxidative str...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129845/ https://ncbi.nlm.nih.gov/pubmed/21521714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00701.2010 |
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