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Biologic activity in a fragment of recombinant human interferon alpha.

To attempt to locate functionally important regions of the interferon (IFN) molecule, recombinant human IFN-alpha 2 was subjected to proteolytic digestion. The bacterial proteinase thermolysin produced two major complementary fragments, HuIFN-alpha 2-(1-110) and HuIFN-alpha 2-(111-153). After reduct...

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Detalhes bibliográficos
Main Authors: Ackerman, S K, Zur Nedden, D, Heintzelman, M, Hunkapiller, M, Zoon, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC344760/
https://ncbi.nlm.nih.gov/pubmed/6199790
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