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Expression of gastrin-releasing peptide is increased by prolonged stretch of human myometrium, and antagonists of its receptor inhibit contractility

Increased uterine stretch appears to increase the risk of preterm labour, but the mechanism is unknown. The aim of this study was to identify factors that mediate the effect of stretch on human myometrium. Myometrial explants, prepared from biopsies obtained at elective caesarean delivery, were eith...

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Autori principali: Tattersall, Mark, Cordeaux, Yolande, Charnock-Jones, D Stephen, Smith, Gordon C S
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447152/
https://ncbi.nlm.nih.gov/pubmed/22411014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.228239
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