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Caspase-Activated Cell-Penetrating Peptides Reveal Temporal Coupling Between Endosomal Release and Apoptosis in an RGC-5 Cell Model

Caspase-activatable cell-penetrating peptide (CPP) probes, designed for efficient cell uptake and specificity via cleavable intramolecular quenched-fluorophore strategies, show promise for identifying and imaging retinal ganglion cell apoptosis in vivo. However, initial cell uptake and trafficking e...

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Bibliografiske detaljer
Main Authors: Johnson, James R., Kocher, Brandon, Barnett, Edward M., Marasa, Jayne, Piwnica-Worms, David
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447108/
https://ncbi.nlm.nih.gov/pubmed/22900707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc300036z
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