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An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging

Apoptosis is required for normal cellular homeostasis and deregulation of the apoptotic process is implicated in various diseases. Previously, we developed a cell-penetrating near-infrared fluorescence (NIF) probe based on an activatable strategy to detect apoptosis-associated caspase activity in vi...

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Detalhes bibliográficos
Main Authors: Maxwell, Dustin, Chang, Qing, Zhang, Xu, Barnett, Edward M., Piwnica-Worms, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672423/
https://ncbi.nlm.nih.gov/pubmed/19331388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800516n
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