The Therapeutic Profile of Rolipram, PDE Target and Mechanism of Action as a Neuroprotectant following Spinal Cord Injury

The extent of damage following spinal cord injury (SCI) can be reduced by various neuroprotective regimens that include maintaining levels of cyclic adenosine monophosphate (cyclic AMP), via administration of the phosphodiesterase 4 (PDE4) inhibitor Rolipram. The current study sought to determine th...

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Detalhes bibliográficos
Main Authors: Schaal, Sandra Marie, Garg, Maneesh Sen, Ghosh, Mousumi, Lovera, Lilie, Lopez, Michael, Patel, Monal, Louro, Jack, Patel, Samik, Tuesta, Luis, Chan, Wai-Man, Pearse, Damien Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446989/
https://ncbi.nlm.nih.gov/pubmed/23028463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043634
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