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Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species

BACKGROUND: Salinomycin is a polyether ionophore antibiotic that has recently been shown to induce cell death in human cancer cells displaying multiple mechanisms of drug resistance. The underlying mechanisms leading to cell death after salinomycin treatment have not been well characterized. We ther...

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Detalhes bibliográficos
Main Authors: Verdoodt, Berlinda, Vogt, Markus, Schmitz, Inge, Liffers, Sven-Thorsten, Tannapfel, Andrea, Mirmohammadsadegh, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446972/
https://ncbi.nlm.nih.gov/pubmed/23028492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044132
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