Salinomycin increases chemosensitivity to the effects of doxorubicin in soft tissue sarcomas

BACKGROUND: Chemotherapy for soft tissue sarcomas remains unsatisfactory due to their low chemosensitivity. Even the first line chemotherapeutic agent doxorubicin only yields a response rate of 18-29%. The antibiotic salinomycin, a potassium ionophore, has recently been shown to be a potent compound...

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Detalhes bibliográficos
Main Authors: Liffers, Sven-T, Tilkorn, Daniel J, Stricker, Ingo, Junge, Christoph Günter, Al-Benna, Sammy, Vogt, Markus, Verdoodt, Berlinda, Steinau, Hans-U, Tannapfel, Andrea, Tischoff, Iris, Mirmohammadsadegh, Alireza
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854645/
https://ncbi.nlm.nih.gov/pubmed/24144362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-490
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