A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

Drug/radiation resistance to treatment and tumor relapse are major obstacles in identifying a cure for cancer. Development of novel agents that address these challenges would therefore be of the upmost importance in the fight against cancer. In this regard, studies show that the antiapoptotic protei...

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Bibliografiska uppgifter
Huvudupphovsmän: Ling, Xiang, Cao, Shousong, Cheng, Qiuying, Keefe, James T., Rustum, Youcef M., Li, Fengzhi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446924/
https://ncbi.nlm.nih.gov/pubmed/23029106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045571
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