Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

BACKGROUND: Sepsis is associated with systemic inflammatory responses and induction of coagulation system. Neutrophil extracellular traps (NETs) constitute an antimicrobial mechanism, recently implicated in thrombosis via platelet entrapment and aggregation. METHODOLOGY/PRINCIPAL FINDINGS: In this s...

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Bibliographic Details
Main Authors: Kambas, Konstantinos, Mitroulis, Ioannis, Apostolidou, Eirini, Girod, Andreas, Chrysanthopoulou, Akrivi, Pneumatikos, Ioannis, Skendros, Panagiotis, Kourtzelis, Ioannis, Koffa, Maria, Kotsianidis, Ioannis, Ritis, Konstantinos
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446899/
https://ncbi.nlm.nih.gov/pubmed/23029002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0045427
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