Severe Acute Respiratory Syndrome Coronavirus Replication Is Severely Impaired by MG132 due to Proteasome-Independent Inhibition of M-Calpain

The ubiquitin-proteasome system (UPS) is involved in the replication of a broad range of viruses. Since replication of the murine hepatitis virus (MHV) is impaired upon proteasomal inhibition, the relevance of the UPS for the replication of the severe acute respiratory syndrome coronavirus (SARS-CoV...

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Détails bibliographiques
Auteurs principaux: Schneider, Martha, Ackermann, Kerstin, Stuart, Melissa, Wex, Claudia, Protzer, Ulrike, Schätzl, Hermann M., Gilch, Sabine
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446591/
https://ncbi.nlm.nih.gov/pubmed/22787216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01001-12
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