Hepatitis C Virus Infection Modulates Expression of Interferon Stimulatory Gene IFITM1 by Upregulating miR-130A

We have examined the underlying mechanism of hepatitis C virus (HCV)-mediated IFITM1 regulation. IFITM1 is a potential target of miR-130a. Our results demonstrated that miR-130a expression was significantly higher in HCV-infected hepatocytes and liver biopsy specimens than in controls. Introduction...

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Autors principals: Bhanja Chowdhury, Joydip, Shrivastava, Shubham, Steele, Robert, Di Bisceglie, Adrian M., Ray, Ranjit, Ray, Ratna B.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Cellular Response to Infection
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446586/
https://ncbi.nlm.nih.gov/pubmed/22787204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00882-12
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