The NS1 Protein of Influenza A Virus Blocks RIG-I-Mediated Activation of the Noncanonical NF-κB Pathway and p52/RelB-Dependent Gene Expression in Lung Epithelial Cells

Influenza A virus (IAV) infection of epithelial cells activates NF-κB transcription factors via the canonical NF-κB signaling pathway, which modulates both the antiviral immune response and viral replication. Since almost nothing is known so far about a function of noncanonical NF-κB signaling after...

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Hlavní autoři: Rückle, Andrea, Haasbach, Emanuel, Julkunen, Ilkka, Planz, Oliver, Ehrhardt, Christina, Ludwig, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446553/
https://ncbi.nlm.nih.gov/pubmed/22787206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00323-12
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