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Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha
INTRODUCTION: The present study assessed the potential functions of interleukin (IL)-32α on inflammatory arthritis and endotoxin shock models using IL-32α transgenic (Tg) mice. The potential signaling pathway for the IL-32-tumor necrosis factor (TNF)α axis was analyzed in vitro. METHODS: IL-32α Tg m...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2012
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3446501/ https://ncbi.nlm.nih.gov/pubmed/22613074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3850 |
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