Statins accelerate the onset of collagen type II-induced arthritis in mice

INTRODUCTION: Statins (hydroxymethylglutaryl coenzyme A reductase inhibitors) are effective in reducing the risk of cardiovascular morbidity and mortality in patients with hyperlipidemia, hypertension, or type II diabetes. Next to their cholesterol-lowering activity, statins have immunomodulatory pr...

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Hauptverfasser: Vandebriel, Rob J, De Jong, Hilda JI, Gremmer, Eric R, Klungel, Olaf H, Tervaert, Jan-Willem Cohen, Slob, Wout, Van Der Laan, Jan Willem, Van Loveren, Henk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446464/
https://ncbi.nlm.nih.gov/pubmed/22537858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3814
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