Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo

INTRODUCTION: The majority of deaths from breast cancer are a result of metastases; however, little is understood about the genetic alterations underlying their onset. Genetic profiling has identified the adhesion molecule plakoglobin as being three-fold reduced in expression in primary breast tumor...

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Detalhes bibliográficos
Main Authors: Holen, Ingunn, Whitworth, Jacob, Nutter, Faith, Evans, Alyson, Brown, Hannah K, Lefley, Diane V, Barbaric, Ivana, Jones, Mark, Ottewell, Penelope D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446349/
https://ncbi.nlm.nih.gov/pubmed/22632416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3201
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