IL-1 drives breast cancer growth and bone metastasis in vivo

BACKGROUND: We have recently identified interleukin 1B (IL-1B) as a potential biomarker for predicting breast cancer patients at increased risk for developing bone metastasis. In mouse models, IL-1B and its receptor (IL-1R1) are upregulated in breast cancer cells that metastasise to bone compared wi...

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Foilsithe in:Oncotarget
Main Authors: Holen, Ingunn, Lefley, Diane V., Francis, Sheila E., Rennicks, Sarah, Bradbury, Steven, Coleman, Robert E., Ottewell, Penelope
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2016
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342762/
https://ncbi.nlm.nih.gov/pubmed/27765923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12289
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