CD44 enhances invasion of basal-like breast cancer cells by upregulating serine protease and collagen-degrading enzymatic expression and activity

INTRODUCTION: Basal-like breast cancers (BL-BCa) have the worst prognosis of all subgroups of this disease. Hyaluronan (HA) and the HA receptor CD44 have a long-standing association with cell invasion and metastasis of breast cancer. The purpose of this study was to establish the relation of CD44 to...

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Detalhes bibliográficos
Main Authors: Montgomery, Nicola, Hill, Ashleigh, McFarlane, Suzanne, Neisen, Jessica, O'Grady, Anthony, Conlon, Susie, Jirstrom, Karin, Kay, Elaine W, Waugh, David JJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446347/
https://ncbi.nlm.nih.gov/pubmed/22621373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3199
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