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Multifunctional G-Rich and RRM-Containing Domains of TbRGG2 Perform Separate yet Essential Functions in Trypanosome RNA Editing

Efficient editing of Trypanosoma brucei mitochondrial RNAs involves the actions of multiple accessory factors. T. brucei RGG2 (TbRGG2) is an essential protein crucial for initiation and 3′-to-5′ progression of editing. TbRGG2 comprises an N-terminal G-rich region containing GWG and RG repeats and a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Foda, Bardees M., Downey, Kurtis M., Fisk, John C., Read, Laurie K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445973/
https://ncbi.nlm.nih.gov/pubmed/22798390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00175-12
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