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TbRGG2 facilitates kinetoplastid RNA editing initiation and progression past intrinsic pause sites

TbRGG2 is an essential kinetoplastid RNA editing accessory factor that acts specifically on pan-edited RNAs. To understand the mechanism of TbRGG2 action, we undertook an in-depth analysis of edited RNA populations in TbRGG2 knockdown cells and an in vitro examination of the biochemical activities o...

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Detalhes bibliográficos
Main Authors: Ammerman, Michelle L., Presnyak, Vladimir, Fisk, John C., Foda, Bardees M., Read, Laurie K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957062/
https://ncbi.nlm.nih.gov/pubmed/20855539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2285510
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