Comparison of male chimeric mice generated from microinjection of JM8.N4 embryonic stem cells into C57BL/6J and C57BL/6NTac blastocysts

To identify ways to improve the efficiency of generating chimeric mice via microinjection of blastocysts with ES cells, we compared production and performance of ES-cell derived chimeric mice using blastocysts from two closely related and commonly used sub-strains of C57BL/6. Chimeras were produced...

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Bibliographic Details
Main Authors: Fielder, Thomas J., Yi, Charles S., Masumi, Juliet, Waymire, Katrina G., Chen, Hsiao-Wen, Wang, Shuling, Shi, Kai-Xuan, Wallace, Douglas C., MacGregor, Grant R.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445772/
https://ncbi.nlm.nih.gov/pubmed/22422470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-012-9605-3
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