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FUNCTIONAL ANALYSIS OF A NOVEL POSITIVE ALLOSTERIC MODULATOR OF AMPA RECEPTORS DERIVED FROM A STRUCTURE-BASED DRUG DESIGN STRATEGY

Positive allosteric modulators of α-amino-3-hydroxy-5-methyl-isoxazole-propionic acid (AMPA) receptors facilitate synaptic plasticity and can improve various forms of learning and memory. These modulators show promise as therapeutic agents for the treatment of neurological disorders such as schizoph...

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Bibliografische gegevens
Hoofdauteurs: Harms, Jonathan E., Benveniste, Morris, Maclean, John K. F., Partin, Kathryn M., Jamieson, Craig
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445766/
https://ncbi.nlm.nih.gov/pubmed/22735771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.06.008
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