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Aflibercept in pediatric solid tumors: moving beyond the trap
Angiogenesis plays a pivotal role in the growth and metastasis of adult and pediatric solid tumors. Clinical investigation of angiogenesis inhibitors is currently underway for childhood cancers. While the pediatric study of aflibercept provides proof of principle, challenges remain in developing cli...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3445740/ https://ncbi.nlm.nih.gov/pubmed/22869868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2212 |
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