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Three-Dimensional Structure and Determinants of Stability of the Iron-Sulfur Cluster Scaffold Protein IscU from Escherichia coli

The highly-conserved protein, IscU, serves as the scaffold for iron-sulfur cluster assembly in the ISC system common to bacteria and eukaryotic mitochondria. The apo-form of IscU from Escherichia coli has been shown to populate two slowly interconverting conformational states: one structured (S) and...

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Autors principals: Kim, Jin Hae, Tonelli, Marco, Kim, Taewook, Markley, John L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445271/
https://ncbi.nlm.nih.gov/pubmed/22734684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300579p
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