BURN-INDUCED GUT BARRIER INJURY IS ATTENUATED BY PHOSPHODIESTERASE INHIBITION: EFFECTS ON TIGHT JUNCTION STRUCTURAL PROTEINS

Loss of intestinal barrier function after burn injury allows movement of intraluminal contents across the mucosa, which can lead to the development of distant organ injury and multiple organ failure. Tight junction function is highly regulated by membrane-associated proteins including occludin and z...

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Main Authors: Costantini, Todd W., Loomis, William H., Putnam, James G., Drusinsky, Dana, Deree, Jessica, Choi, Sunghyuk, Wolf, Paul, Baird, Andrew, Eliceiri, Brian, Bansal, Vishal, Coimbra, Raul
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445035/
https://ncbi.nlm.nih.gov/pubmed/18791495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181863080
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